Head on over to Paul Knoepfler’s blog and check out hisYamanaka Interview on Clinical Use of Pluripotent Stem Cells.
I don’t know. I’ll be posting more about this tomorrow, but… suffice it to say right now that I wish I could get more excited about this new study with iPSC’s. I think they’re rushing wayyyyyy too fast to use these techniques on a human subject, especially when you look at all the pre-clinical problems and questions. And there were A LOT.
And I think we could have all lived without this quote:
At the same time, the ethical issues that hESC possess mean that as iPSC technology improves, hESC will be less needed. Still, iPSC is a new technology, and its safety and efficacy still needs to be confirmed.
Um, hello, EARTH TO DR. YAMANAKA. There ARE no “ethical issues.” Seriously, you don’t know about Robert Lanza’s blastomere technique, which doesn’t destroy the embryo?. And yep, no kidding that iPSC’s safety needs to be confirmed, much less their efficacy. Maybe we shouldn’t be blithely testing these cells on human beings right now.
That’s enough of a rant for today, but there will be more tomorrow!